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Although the rates of allergic reaction in patients on topical CAI were higher in those with a prior sulfa allergy than in those without, there were no significant differences in rates among patients with other prior non-sulfa-based allergic reactions

Nat Med (2016) 22(1):10513

DSIP is a naturally occurring peptide in the body, primarily found in the hypothalamus

The purpose of this brief opinion is to identify critical elements that can respond rapidly to an acute inflammatory and oxidative stress response and to suggest how these key elements can be supplemented in unison to improve the efficacy of any one pathway individually