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Important enzymes and cofactors are ATP synthase (complex V), cytochrome c oxidase (complex IV), NADH DH (complex I), pyruvate DH, and cofactors like NAD+/NADH and FAD

(2010) 5:e11519

Following recruitment to sites of endothelial dysfunction, both monocyte-derived macrophages and resident intimal macrophages take up modified LDL and form foam cells that contribute to inflammatory processes within the plaque (132)