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According to a 2021 study, most of the symptoms of fibromyalgia including fatigue and increased pain sensitivity are caused by the abnormal increase in the activity of pain-sensing nerves throughout the body Overactivity in the immune system usually occurs after an infection or injury, and it is caused by the presence of certain antibodies

These three clusters are not influenced by age at first DE onset, cumulative duration, or types of depression, but it is cerebrovascular and cardiovascular diseases and physical symptoms associated with them, i.e

Elife 10, e62203