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In addition, it was found that this sdAb specifically binds to the tumor and does not spread to healthy tissue, resulting in a high tumor/normal tissue ratio

Cellular studies have shown that exogenous NAD + can impact mitochondrial activity, such as boosting Krebs cycle and the ETC, but also impair genomic DNA replication and induce DNA replication stress due to impairment of pyrimidine biosynthesis 118