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E-cigarettes generally contain nicotine, a type of flavoring (molasses and fruit are common) and propylene glycol - a manufactured liquid used in food, cosmetics, and certain medicines to absorb water and help them retain moisture

The rise of e-cigarettes has introduced a plethora of new terminology into our lexicon, often involving e cigarette synonyms that serve to describe these popular vaping devices

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Furthermore, the nicotine concentration level (~ 6.57 g/ml) obtained per well in our studies related with previous smoke exposure reports utilizing the 1R6F cigarettes 57,58 , although future in-depth studies are required to standardize the in vitro to in vivo smoker dose correlation to better assess human smoking responsiveness