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Where nic salt e-liquid is different is through the addition of benzoic acid, which enables the nicotine content, even at higher levels, to be vaped with a much smoother hit, and at relatively low temperatures, ie without needing to adjust the temperature, hence the suitability to non-variable/non-adjustable devices such as pod systems and AIO kits

It can still interact with your medication because both are processed by the same group of enzymes in your liver (the CYP450 system)

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A New York Times article from December 1888 noted that cigarette manufacturers frequently offered premiums that enticed boys to excessive cigarette smoking. A tobacco dealer from the era said that any Saturday afternoon a crowd of children with vouchers would besiege tobacco shops, clamoring for the reward of self-inflicted injury. Duke also used celebrity endorsements from famous ballplayers such as Christy Mathewson and Ty Cobb for his various brands of tobacco products