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The trends in the death rates from lung cancer in various age groups from 1960 to 2010 have been reasonably similar in the US and Canada, which is expected given the similarities in the causes of death (World Health Organization, 2016), smoking patterns (Figure 1), and the procedures for certifying both death and lung cancer in the two countries

Dual use refers to using both e-cigarettes and traditional cigarettes simultaneously

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It would be of importance to study if p-benzoquinone, nicotyrine, and other flavoring chemicals identified at higher concentrations in this study are responsible for the detected toxicological response observed in bronchial and alveolar mucosa models