Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide DOTA bifucational chelator containing a

DOTA bifucational chelator containing a carboxylic acid group

1038/nchem

Product Name Lissamine rhodamine B PEG3 azide Synonyms Sulforhodamine B PEG3 azide CAS Number N/A Related CAS Molecular Formula C35H46N6O9S2 Molecular Weight 758

031 Purity (HPLC) >= 95% Solubility DMSO

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide DOTA bifucational chelator containing aSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine