Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4)-Exatecan Size:25mg Product Name Azide-Dap(m-PEG4)-Val-Cit-OH Synonyms CAS

Product Name Azide-Dap(m-PEG4)-Val-Cit-OH Synonyms CAS Number Related CAS Molecular Formula C24H44N8O10 Molecular Weight 604

O=C(N1CCNCC1)C1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC): 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

NCCOCCN1CCN(CC1)C1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) 95% Shipping Conditions Room Temperature Storage Conditions Refrigerated Regulatory Statemen: For Research Use Only

AggFluor P1 exhibits fluorescence in both misfolded oligomers and insoluble aggregates but cannot differentiate between these species

Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4)-Exatecan Size:25mg Product Name Azide-Dap(m-PEG4)-Val-Cit-OH Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I