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View on PubMed Investigation of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Selective MC4R Agonist Characterised the pharmacokinetics and appetite-suppressing pharmacodynamics of a selective MC4R agonist in clinical subjects, providing mechanistic context for Melanotan II's effects on appetite and energy balance (J Clin Pharmacol, 2014)

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Description Melanotan 2 (MT-2) Research Peptide (10 mg) Melanotan 2 (MT-2) is a synthetic cyclic heptapeptide analogue of endogenous -melanocyte-stimulating hormone (-MSH), developed at the University of Arizona as a structurally minimized, conformationally constrained derivative designed to improve metabolic stability and receptor selectivity relative to the native hormone and its linear analogue Melanotan 1

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