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Key challenges include ensuring long-term sensor stability and antifouling performance in complex biofluids, as well as achieving reproducible and scalable manufacturing

Next, samples were centrifuged at 17,000 g for 10 min and 800 l supernatant was dried in a vacuum evaporator (Thermo)

Jean et al., 2019)

Cooperation of condensin and mediator to form mitotic chromosome architecture By comparing Hi-C data from Cnd1-Pmc4 double depletion with that from Cnd1 or Pmc4 single depletion, we find that condensin primarily contributes to genomic contacts within approximately 800 kb, whereas mediator appears to exert an inhibitory effect on genomic contacts within roughly 800 kb (Supplementary Fig