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Discovery of GluN2A-Selective NMDA receptor positive allosteric modulators (PAMs): tuning deactivation kinetics via structure-based design

Similarly, elevated methylation in the RELN promoter reduced RELN expression, particularly in the prefrontal cortex and cerebellum of ASD patients, potentially impairing neurodevelopment and impaired synaptic plasticity (Lammert and Howell, 2016

Abbreviation: AMPK, adenosine monophosphate activated protein kinase

In contrast to initial reports placing GSH synthesis to both plastids and cytoplasm, the first enzyme of the pathway, -glutamylcysteine synthetase, is strictly localized in plastids, at least in Arabidopsis (Wachter et al., 2005)