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29,30 In 1985, oxidative stress was defined as a cellular imbalance between oxidants and reductants, leading to the differentiation of eustress and distress to describe oxidative stress states under physiological and pathological conditions, thereby advancing our understanding of oxidative stress in human diseases

Karin O, Raz M, Tendler A, Bar A, Kohanim YK, Milo T, et al

GSH S-conjugates can be considered as tertiary metabolites as opposed to the essential primary metabolites and the secondary ones, which are biosynthesized upon need

Antioxidant Defense Glutathione is often referred to as the body's "master antioxidant." It helps neutralize free radicals and reactive oxygen species (ROS), preventing oxidative damage to cells