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Further experiments revealed that Cx43 was colocalizing with ER marker (calnexin), revealing the inability of Cx43 to be transported beyond endoplasmic reticulum/endoplasmic reticulum Golgi intermediate compartment (ER/ERGIC) (Hussain et al., manuscript communicated)

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also, diet - namely, ethanol intake - and high fat and/or high protein diet seems to favor ROS production [10]