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The ATRA-dependent overexpression of the glutamate transporter EAAC1 requires RARbeta induction

Despite the beneficial effects of reactive astrocytes, there is growing evidence that they adopt a detrimental profile under chronic stress

This is mainly the result of the antioxidant effects of the N-acetylcysteine

Nature Reviews Gastroenterology & Hepatology 14, 397411.CrossRefGoogle ScholarPubMed Vakrakou, AG, Boiu, S, Ziakas, PD, Xingi, E, Boleti, H, and Manoussakis, MN (2018) Systemic activation of NLRP3 inflammasome in patients with severe primary Sjgrens syndrome fueled by inflammagenic DNA accumulations